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Cystic fibrosis (CF) is a common hereditary disease that affects the entire body, causing progressive disability and early death. Breathing difficulties are the most common symptom and result from frequent lung infections, which are treated, though not always cured, by antibiotics and other medications. CF is a multi-system disorder of exocrine glands causing the formation of a thick mucus substance that affects the lungs, intestines, pancreas, and liver. The standard test for diagnosis is a sweat test which evaluates the level of chloride excreted by the body. A multitude of symptoms, including sinus infections, poor growth, diarrhea and infertility, result from the effects of CF on other parts of the body.

CF is one of the most common fatal inherited disease. It is most prevalent among Caucasians and Ashkenazi Jews; one in 25 people of European descent carries one gene for CF, making it the most common genetic disease among them. Individuals with cystic fibrosis can be diagnosed prior to birth by genetic testing or in early childhood by a sweat test. There is no cure for CF, and the current median age of survival for patients living in the U.S. is 36.8 years. Ultimately, lung transplantation is often necessary as CF worsens.

CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator (CFTR). This gene helps create sweat, digestive juices, and mucus. Although most people without CF have two working copies of the CFTR gene, only one is needed to prevent cystic fibrosis. CF develops when neither gene works normally. Therefore, CF is considered an autosomal recessive disease. The name cystic fibrosis refers to the characteristic scarring (fibrosis) and cyst formation within the pancreas, first recognized in the 1930s.Andersen DH. Cystic fibrosis of the pancreas and its relation to celiac disease: a clinical and pathological study. Am J Dis Child 1938; 56:344-399

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praying 4 a cure for cystic fibrosis. my daughter Eliza and many friends of ours are fighting 4 their lives. cure cf! www.cff.org
angels4eliza (Joanna McVicker) Tue, 03 Nov 2009 07:00:23 -0000
praying 4 a cure for cystic fibrosis. my daughter Eliza and many friends of ours are fighting 4 their lives. cure cf! www.cff.org
Organise sponsorship for women duathlon for cystic fibrosis. Please sponsor me. http://www.fundraiseonline.co.nz/LaniPham/
okinichan (Lani Pham) Tue, 03 Nov 2009 06:21:19 -0000
Organise sponsorship for women duathlon for cystic fibrosis. Please sponsor me. http://www.fundraiseonline.co.nz/LaniPham/
Pizzazz will b @balt wine opener this friday at musuem of industry 4 Cystic Fibrosis
pizzzazz (Pizzazz ) Tue, 03 Nov 2009 05:36:24 -0000
Pizzazz will b @balt wine opener this friday at musuem of industry 4 Cystic Fibrosis
RT @camarillos6: please sign to help Caley w/ Cystic Fibrosis DREAM come true b4 its too late! http://twitition.com/uiwyk come on ppl!
katerz1222 (Katerz) Tue, 03 Nov 2009 02:54:04 -0000
RT @camarillos6: please sign to help Caley w/ Cystic Fibrosis DREAM come true b4 its too late! http://twitition.com/uiwyk come on ppl!
Attending the CF Cystic Fibrosis charity wine tasting & dinner at the Baltimore Museum of Industry on Friday. www.thebmi.org
PIXELSEED (Pixelseed) Tue, 03 Nov 2009 01:55:48 -0000
Attending the CF Cystic Fibrosis charity wine tasting & dinner at the Baltimore Museum of Industry on Friday. www.thebmi.org
Completed production on a CF Cystic Fibrosis promotional video. I lan to edit & ready by the end of the this week.
PIXELSEED (Pixelseed) Tue, 03 Nov 2009 01:53:06 -0000
Completed production on a CF Cystic Fibrosis promotional video. I lan to edit & ready by the end of the this week.

 
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Boomer Esiason Foundation: What is Cystic Fibrosis? - Description of the symptoms of CF, causes, treatments, and current research.
Meta Description: [ The Boomer Esiason Foundation Home page contains cystic fibrosis news and BEF Highlights. ]

Cystic Fibrosis Foundation - Provides information about the disease, treatment options, clinical trials, research, and public policy.
Meta Description: [ cff.org, Home ]

KidsHealth: Cystic Fibrosis - Learn more about this condition, the causes, and what it is like to live with CF.
Meta Description: [ Cystic fibrosis affects the lungs and makes it hard to breathe. Find out more in this article for kids. ]

KidsHealth: Recipes for Kids With Cystic Fibrosis - Learn to make these high-calorie recipes, like cheesecake squares, cheesy mashed potatoes, and baked creamy chicken.
Meta Description: [ These high-calorie recipes are especially for kids with cystic fibrosis (CF). Kids with CF may need additional calories to meet their nutritional needs. Check out these delicious recipes. ]

TeensHealth: Cystic Fibrosis - Learn about what it is, the causes, what happens to the body, and how to live with it.
Meta Description: [ Cystic fibrosis (CF) is an inherited disease that causes the body to produce mucus that's extremely thick and sticky. It mainly affects the lungs and the pancreas, causing serious breathing and digestive problems. ]

TeensHealth: Cystic Fibrosis Diet and Nutrition - Learn what CF teens need to eat more of, supplements that help, and a sample diet.
Meta Description: [ Like every other teenager, girls and guys with CF need calories to fuel their growth. They just need more of them - sometimes as much as 30% to 50% more calories than other teens. ]

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