Down syndrome (also Down's syndrome) or trisomy 21 or I R GOT DOWNS NOW LOL is a genetic condition resulting from the presence of all or part of an extra 21st chromosome. Down syndrome is characterized by a combination of major and minor abnormalities of body structure and function. Among features present in nearly all cases are impairment of learning and physical growth, and a recognizable facial appearance usually identified at birth. It is named after John Langdon Down, the British doctor who first described it in 1866.
Children with Down syndrome have lower than average cognitive ability, normally ranging from mild to moderate retardation. The common physical features of Down syndrome also appear in people with a standard set of chromosomes. They include simian crease (a single crease across one or both palms), almond shaped eyes, shorter limbs, speech impairment, and enlarged tongue. In addition, health concerns for children with Down syndrome include a higher risk for congenital heart defects, gastroesophageal reflux disease, recurrent ear infections, obstructive sleep apnea, and thyroid disfunctions.
Early childhood intervention, screening for common problems, such as thyroid functioning, medical treatment where indicated, a conducive family environment, vocational training, etc., can improve the overall development of children with Down syndrome. Experience with children with Down syndrome shows that while some genetic limitations cannot be overcome, education and proper care can produce excellent progress whatever the starting point. The commitment of parents, teachers, and therapists to individual children has produced previously unexpected positive results.
More on [ Down syndrome ]

KidsHealth: Down Syndrome - Learn about this genetic disorder, the causes, other health problems that can happen, and what life is like.
Meta Description: [ What's up with Down syndrome? ]
Stories About People with Down Syndrome - Short articles about the lives of real people with Down syndrome, written by family, friends, and occasionally by people with this condition. Includes photos.
Suj's Site - Born with Down syndrome, Sujeet is a musician, black belt in Tae Kwan Do, and a World Game special Olympian. Listen to his music and read his inspiring story.
ThinkQuest: Down Syndrome - Features a young student who has Down Syndrome, class experiences, history, and education.
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